Pesquisa sobre:
CYTOCHROME P-450 CYP1B1
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Cytochrome P-450 CYP1B1
Descritor
Espanhol
:
citocromo P-450 CYP1B1
Descritor
Português
:
Citocromo P-450 CYP1B1
Sinônimos
Inglês
:
Cytochrome P 450 CYP1B1
Cytochrome P450 CYP1B1
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
Cytochrome P4501B1
P450 CYP1B1, Cytochrome
Categoria:
D08.244.453.005.500
D08.244.453.100.875
D08.811.682.690.708.170.010.500
D08.811.682.690.708.170.020.875
D12.776.422.220.453.010.500
D12.776.422.220.453.100.875
Definição
Inglês
:
A
cytochrome
P450 aryl hydrocarbon hydroxylase that has specificity for
ESTROGENS
which it converts into 4-hydroxy
estrogens
. CYP1B1 has been shown to be physiologically important for
FETAL DEVELOPMENT
with
mutations
in the CYP1B1 gene resulting in congenital forms of
GLAUCOMA
and Peter's anomaly.
Nota de Indexação
Inglês
:
/antag: coordinate with
CYTOCHROME P-450 ENZYME INHIBITORS
Nota Histórica
Inglês
:
2015
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
55605
Identificador Único:
D065633
Ocorrência na BVS
:
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